本书分为三大部分，共11个章节。
第一部分（第一章）浓缩记录了历次全球传染病大流行。分别回顾了鼠疫、霍乱、天花、流感、新冠肺炎等历次全球传染病大流行的严重危害，分析了中东呼吸综合征、埃博拉病毒病、SARS等可能导致大流行的传染病威胁。
第二部分（第二章至第七章）荟萃了人类对传染病大流行的最新科学认识。系统阐释了大流行的实现途径、大流行的挑战、病原体跨种传播、基于基因测序的病原体监测与预警、气候变化对大流行的威胁及全球化与大流行。
第三部分（第八章至第十一章）凝练了全球应对传染病大流行的策略和经验。介绍了大流行防范与应对的策略和措施；以新冠肺炎疫情为例，总结了全球应对新冠肺炎大流行的干预措施及中国抗疫经验。
本书为英文版。

Chapter 1 Pandemic Threats
I.The Plague
II.Cholera
III.Smallpox
IV.Influenza
V.COVID-19
VI.Other infectious diseases that may cause pandemics
References
Chapter 2 How Pandemics Arise
I.Characteristics of pandemics and determination criteria
II.Characteristics of pandemic-inducing infectious diseases
III.Factors contributing to pandemics of infectious diseases
References
Chapter 3 The Challenges of Pandemics
I.Absence of a unified global community of interest
II.Monitoring systems insufficient for early warning and response
III.Lack of urgency and targeted measures early in the pandemic
IV.Overburdened healthcare providers and lack of effective drugs
V.Inequitable vaccine distribution and vaccine hesitation
VI.Ineffective public education and social stigma and discrimination
VII.Shortage of other diseases prevention and control services
References
Chapter 4 Cross-Species Transmission of Pathogens
I.Risk of cross-species transmission of pathogens
II.Challenges of cross-species transmission of pathogens
III.Studies on SARS-CoV-2 hosts
IV.Risk assessment of cross-species transmission of pathogens
References
Chapter 5 Genetic Sequencing-Based Pathogen Surveillance and Early Warning Systems
I.Methods for monitoring pathogenic variation
II.Pathogen genome surveillance network and data sharing system
III.Bioinformatic prediction and warning of pathogenicity variations
References
Chapter 6 The Threat of Climate Change to Pandemics
I.Climate change and pandemics
II.The impact of climate factors on the COVID-19 pandemic
III.Strategies to cope with the risk of infectious diseases under climate change
References
Chapter 7 Globalization and Pandemics
I.The impact of globalization on pandemics
II.The impact of pandemics on globalization
III.The Chinese approach to addressing globalization and pandemics
References
Chapter 8 Pandemic Preparedness
I.Surveillance of and preparedness for animal-origin pathogens with pandemic potential
II.Policy and coordination mechanisms
III.Basic capacity building
IV.Scientific research
V.Workforce and talent training and reserve
References
Chapter 9 Pandemic Response and Assessment
I.PHEIC response and assessment
II.Assessment of pandemic response capacity
References
Chapter 10 The COVID-19 Pandemic
I.The COVID-19 outbreak
II.Epidemiological characteristics of the SARS-CoV
III.Identification of SARS-CoV-2 pathogens
IV.Origin tracing of SARS-CoV
V.COVID-19 prevention and control measures and their effectiveness
VI.Reflections and outlook
References
Chapter 11 China’s Experience in the Prevention and Control of
COVID-19 and Its Contribution to the World
I.The four phases of China’s COVID-19 prevention and controlefforts
II.China’s experience in the prevention and control of COVID-19
III.China’s contribution to the world through its response to COVID-19
References
Acknowledgments